
A healthcare professional reviews structured clinical and administrative data with AI support, illustrating how Claude is designed to operate inside regulated healthcare workflows rather than replacing human decision-making. Image Source: ChatGPT-5.2
Anthropic Launches HIPAA-Ready Claude Agents and Tools for Healthcare and Life Sciences
Anthropic is announcing a major expansion of Claude into healthcare and life sciences, introducing HIPAA-ready tools, new medical data connectors, and agent capabilities designed for use across clinical care, healthcare operations, and regulated scientific workflows.
The announcement builds on Anthropic’s October launch of Claude for Life Sciences, which positioned Claude as a research partner for scientists and clinicians working in preclinical research and early development. That initial release focused primarily on supporting discovery-oriented tasks.
With this update, Anthropic is extending Claude’s role in two key ways. The company is launching Claude for Healthcare, a complementary offering that enables healthcare providers, payers, and patients to use Claude for medical purposes through HIPAA-ready products. At the same time, Anthropic is expanding Claude’s life sciences capabilities by connecting it to additional scientific platforms and supporting workflows that span clinical trial management, regulatory operations, and drug discovery.
Anthropic says these expansions are made possible by recent improvements in Claude’s underlying intelligence, particularly its performance on agent-based simulations of medical and scientific tasks. The focus, the company argues, is not conversational AI, but whether Claude can reliably execute complex, high-stakes tasks in real-world, regulated environments.
Key Takeaways: Claude for Healthcare and Life Sciences
Anthropic launches Claude for Healthcare, enabling HIPAA-ready AI use for providers, payers, startups, and patients.
Claude Opus 4.5 demonstrates strong performance on medical agent benchmarks, including MedAgentBench and MedCalc Bench.
New healthcare data connectors support prior authorization, claims appeals, ICD-10 coding, and provider verification.
Expanded Claude for Life Sciences capabilities support clinical trials, regulatory submissions, and drug discovery workflows.
Personal health integrations allow patients to securely summarize and understand their own health data without training the model.
Claude Opus 4.5 Performance on Medical Agent Benchmarks
Anthropic says these product expansions are enabled by recent improvements in Claude’s general intelligence, particularly its performance on agent-based medical simulations that reflect real-world workflows.
According to Anthropic’s evaluations:
Claude Opus 4.5 achieved 92.3% accuracy on MedAgentBench, which measures medical agent task completion
On MedCalc Bench, which evaluates medical calculation accuracy using code execution, Opus 4.5 reached 61.3%, significantly outperforming earlier Claude models
Anthropic also reports improved performance on internal honesty evaluations when Opus 4.5 is used with extended reasoning, reflecting progress in reducing factual hallucinations.
The company frames these gains in practical terms. Anthropic says the improved agentic performance allows Claude to support real-world outcomes such as accelerating prior authorization reviews so patients can access life-saving care more quickly, assisting with care coordination to reduce administrative burden on clinicians, and supporting regulatory submissions so new drugs can reach the market faster.
Rather than treating benchmark performance as an abstract measure, Anthropic is positioning these results as indicators of whether Claude can reliably operate inside high-stakes, regulated healthcare and life sciences environments.
Evaluation notes: Claude 4.5 models were tested using extended reasoning (64k tokens) and native tool use. MedAgentBench is a Stanford-affiliated benchmark.
Claude for Healthcare: HIPAA-Ready AI for Clinical and Administrative Use
What’s New
Claude for Healthcare is a new, complementary offering that allows healthcare organizations to use Claude for medical purposes through HIPAA-ready products.
At the core of the release are new connectors that allow Claude to securely access industry-standard healthcare systems and databases, reducing the time clinicians and administrators spend locating and cross-referencing information.
New Healthcare Connectors
Claude can now connect to:
Centers for Medicare & Medicaid Services (CMS) Coverage Database
Includes both Local Coverage Determinations (LCDs) and National Coverage Determinations (NCDs). This connector enables Claude to verify Medicare coverage requirements at the national and local level, support prior authorization checks, and help assemble stronger claims appeals. Anthropic says the integration is designed to support revenue cycle management, compliance teams, and patient-facing staff working with Medicare policy.International Classification of Diseases, 10th Revision (ICD-10)
Allows Claude to look up diagnosis and procedure codes to support medical coding, billing accuracy, and claims management. The ICD-10 data used by Claude is provided by the Centers for Medicare & Medicaid Services (CMS) and the Centers for Disease Control and Prevention (CDC), enabling alignment with widely used clinical and billing standards.National Provider Identifier (NPI) Registry
Enables Claude to assist with provider verification, credentialing, network directory management, and claims validation by referencing the national registry of healthcare providers maintained in the United States.
HIPAA-compliant organizations using Claude for Enterprise can also access existing healthcare-related connectors, including PubMed, which provides access to more than 35 million biomedical research articles for up-to-date literature reviews and clinical context.
Claude Agent Skills for Healthcare Operations and Workflows
Anthropic is also introducing two new agent skills designed to support common healthcare integration and administrative tasks.
Fast Healthcare Interoperability Resources (FHIR) Development Skill
Supports development using the Fast Healthcare Interoperability Resources (FHIR) standard, the modern framework for exchanging data between healthcare systems. Anthropic says this skill is intended to improve interoperability by helping developers connect electronic health record systems and other healthcare platforms more quickly and with fewer integration errors.Prior Authorization Review Skill (Sample)
Provides a customizable template that organizations can adapt to their own policies and workflows for reviewing prior authorization requests. The skill supports cross-referencing between coverage requirements, clinical guidelines, patient records, and appeal documentation, with the goal of reducing manual review time and improving consistency across authorization decisions.
Healthcare Operations Use Cases: Prior Authorization, Claims, and Care Coordination
With these tools, Anthropic is positioning Claude as an operational support layer designed to address some of the most time-consuming and error-prone healthcare workflows.
Example Use Cases
Prior Authorization Reviews
Prior authorization requests can take hours to review and often delay patient access to care, creating frustration for both providers and payers. These reviews typically require navigating fragmented information sources, including coverage requirements, clinical guidelines, patient records, and appeal documentation. Anthropic says Claude can pull coverage requirements from the Centers for Medicare & Medicaid Services (CMS) or organization-specific policies, check clinical criteria against patient records in a HIPAA-ready environment, and propose determinations with supporting documentation for payer review.Claims Appeals Support
Denied claims impose significant time and financial costs across the healthcare system. By aggregating patient records, coverage policies, clinical guidelines, and prior documentation, Claude can help providers prepare more complete and consistent appeals while enabling payers to review them more efficiently.Care Coordination and Patient Messaging
Care teams often manage high volumes of patient portal messages, referrals, and handoffs, increasing the risk that urgent issues are delayed or overlooked. Anthropic says Claude can help triage incoming messages, identify items requiring immediate attention, and support smoother care coordination.Healthcare Product Development
On the Claude Developer Platform, startups and healthcare technology teams can build new products aimed at reducing administrative burden across clinical workflows, including ambient clinical documentation, chart review assistance, and clinical decision-support tools.
Personal Health Data Integrations for Patients
Anthropic is also expanding Claude’s role for individual users by introducing new health data integrations designed to help people better understand their personal health information and prepare for more informed conversations with clinicians.
In the United States, Claude Pro and Claude Max subscribers can choose to give Claude secure access to their personal health data, including lab results and medical records.
New Consumer Health Integrations
HealthEx and Function (beta)
Apple Health and Android Health Connect (rolling out in beta via Claude iOS and Android apps)
When connected, Claude can:
Summarize medical history
Explain test results in plain language
Identify patterns across fitness and health metrics
Help users prepare questions for medical appointments
Anthropic emphasizes that these integrations are opt-in, permission-controlled, and private by design. User health data is not used to train models, and Claude includes contextual disclaimers directing users to healthcare professionals for personalized guidance.
Claude for Life Sciences: Clinical Trials, Regulatory, and Drug Discovery
What’s New
Following its initial focus on preclinical research and development — including bioinformatics work and the generation of scientific hypotheses and research protocols — Anthropic is extending Claude for Life Sciences into later stages of the drug development pipeline.
The expanded capabilities are designed to support clinical trial operations, regulatory workflows, and drug discovery, moving Claude beyond early research assistance and into areas where scientific, operational, and compliance requirements intersect.
New Life Sciences Connectors
Claude can now connect to:
Medidata
A leading provider of clinical trial solutions for the life sciences industry. Through Medidata, organizations can give Claude access to clinical trial data, enrollment metrics, and site performance information, enabling support for trial monitoring, operational oversight, and early identification of timeline risks.ClinicalTrials.gov
The U.S. clinical trials registry, which provides Claude with structured information on drug and device development pipelines. Anthropic says this integration can support patient recruitment planning, site selection, competitive landscape analysis, and protocol design across therapeutic areas.ToolUniverse
Allows scientists to access a library of more than 600 vetted scientific tools. When connected, Claude can help researchers test hypotheses, compare analytical approaches, and refine experimental workflows without manually switching between tools.bioRxiv and medRxiv
The life sciences preprint servers that host early-stage research ahead of formal peer review. Connecting Claude to bioRxiv and medRxiv allows it to surface the latest findings and emerging research trends before they appear in traditional journals.Open Targets
Supports the systematic identification and prioritization of potential therapeutic drug targets by integrating genetic, genomic, and biomedical data. Anthropic positions this connector as a way for Claude to assist researchers in evaluating target viability earlier in the discovery process.ChEMBL
A bioactive compound and drug database that enables Claude to support early discovery and medicinal chemistry research by providing structured data on compound activity, drug properties, and bioassay results.Owkin Pathology Explorer
An agent that analyzes tissue images to detect cells and map tumors. Anthropic says this integration is designed to accelerate drug discovery and development by supporting pathology-driven insights and image-based analysis.
These additions expand Claude’s existing integrations with Benchling, 10x Genomics, PubMed, BioRender, Synapse.org, and Wiley Scholar Gateway. Anthropic also notes that the Benchling connector is now available via Claude.ai on the web with single sign-on (SSO) access.
Claude Agent Skills for Life Sciences and Regulatory Workflows
Anthropic is adding new agent skills designed to support scientific research, clinical development, and regulatory preparation across the life sciences.
Scientific Problem Selection
Supports researchers in identifying and prioritizing scientific questions based on available data, research objectives, and development constraints.Conversion of Instrument Data to Allotrope
Enables the conversion of laboratory instrument data into the Allotrope Data Format, supporting data standardization and downstream analysis across scientific systems.Bioinformatics Workflows Using scVI-tools and Nextflow
Provides skills bundles that support bioinformatics analysis and workflow orchestration using scVI-tools and Nextflow, helping teams deploy and manage complex computational pipelines more efficiently.Clinical Trial Protocol Draft Generation (Sample Skill)
Supports the drafting of clinical trial protocols, including endpoint recommendations, while accounting for regulatory pathways, the competitive landscape, and relevant U.S. Food and Drug Administration (FDA) guidelines.
Life Sciences Use Cases: Clinical Trials and Regulatory Submissions
With these tools, Claude can support:
Clinical Trial Protocol Drafting
Claude can create draft clinical trial protocols that take U.S. Food and Drug Administration (FDA) and National Institutes of Health (NIH) requirements into account, while incorporating an organization’s preferred templates, internal policies, and existing datasets.Clinical Trial Operations
Using Medidata trial data, Claude can track operational indicators such as enrollment progress and site performance, allowing teams to surface potential risks before they affect trial timelines, site productivity, or patient recruitment goals.Regulatory Submissions
Claude can assist with regulatory submissions by identifying documentation gaps, drafting responses to regulatory agency queries, and helping teams navigate FDA guidelines, with the goal of reducing friction during regulatory review.
Getting Started With Claude for Healthcare and Life Sciences
Anthropic says organizations interested in Claude for Healthcare and the expanded Claude for Life Sciences capabilities can access documentation and tutorial resources outlining available connectors, agent skills, and supported workflows.
The new healthcare and life sciences connectors and agent skills are generally available to Claude subscribers across Pro, Max, Teams, and Enterprise plans, according to the company.
Organizations evaluating Claude for use in clinical, operational, or regulated environments can also contact Anthropic to discuss enterprise deployments and implementation options.
Q&A: Claude for Healthcare and Life Sciences
Q: What is Claude for Healthcare?
A: Claude for Healthcare is Anthropic’s HIPAA-ready deployment of Claude, designed for use by healthcare providers, payers, startups, and patients across clinical, administrative, and operational workflows.
Q: How does Anthropic address accuracy risks in healthcare AI?
A: Anthropic emphasizes agent-based task execution, extended reasoning, and explicit uncertainty handling, rather than summary-style responses. Claude is designed to reference source systems, acknowledge limitations, and defer to clinicians for medical decisions.
Q: What healthcare tasks can Claude support today?
A: Claude can assist with prior authorization reviews, claims appeals, care coordination, medical coding, clinical documentation support, and patient message triage in HIPAA-ready environments.
Q: How is Claude used in life sciences?
A: Claude for Life Sciences supports clinical trial protocol drafting, trial operations monitoring, regulatory submissions, bioinformatics workflows, and early drug discovery through secure data connectors and agent skills.
Q: Does Anthropic use patient health data to train its models?
A: No. Anthropic states that personal health data accessed through Claude is opt-in, permission-controlled, and not used to train models.
What This Means: Healthcare AI Requires Accuracy, Accountability, and Operational Fit
Anthropic’s expansion reflects a broader push to move AI in healthcare beyond experimentation and into operational systems where accuracy, compliance, and accountability matter.
The timing is notable. It comes as concerns grow around consumer-facing AI tools — particularly search-based AI summaries — surfacing incorrect or misleading health information without sufficient context, safeguards, or professional oversight. In healthcare, authoritative-sounding answers without traceability can introduce real risk.
Anthropic is positioning Claude differently. Rather than generating health answers at the top of search results, Claude is being embedded into structured workflows, connected directly to source systems, and designed to acknowledge uncertainty and defer to clinicians and regulators. This reflects an understanding that healthcare AI fails not because it lacks intelligence, but because it is often deployed without accountability.
By focusing on prior authorization, claims workflows, clinical trials, and regulatory submissions, Anthropic is framing Claude as infrastructure for high-stakes decision support rather than a standalone assistant. The emphasis on HIPAA-ready deployments, agent-based task execution, explicit uncertainty handling, and professional hand-offs suggests an attempt to align AI capabilities with the realities of regulated healthcare environments.
Even with these safeguards, Anthropic’s approach implicitly acknowledges that workflow-embedded AI still requires human oversight, particularly in clinical and regulatory settings where accountability ultimately rests with professionals, not systems.
For healthcare organizations and life sciences companies, the takeaway is less about AI novelty and more about whether these systems can reliably reduce administrative friction without introducing new risk — a test that will increasingly define enterprise AI adoption in medicine.
Sources:
Anthropic – Advancing Claude in Healthcare and the Life Sciences
https://www.anthropic.com/news/healthcare-life-sciencesAnthropic / Claude – Claude for Healthcare
https://claude.com/solutions/healthcareAnthropic / Claude – Healthcare Tutorials and Resources
https://claude.com/resources/tutorials-category/healthcareAnthropic / Claude – Claude for Life Sciences
https://claude.com/solutions/life-sciencesAnthropic / Claude – Life Sciences Tutorials and Resources
https://claude.com/resources/tutorials-category/life-sciencesAnthropic – Claude for Life Sciences Announcement
https://www.anthropic.com/news/claude-for-life-sciencesAnthropic / Claude Platform – Agent Skills Overview
https://platform.claude.com/docs/en/agents-and-tools/agent-skills/overviewAnthropic / Claude Customers – Banner Health Case Study
https://claude.com/customers/banner-healthAnthropic / Claude Customers – Novo Nordisk Case Study
https://claude.com/customers/novo-nordiskAnthropic – Contact Sales
https://www.claude.com/contact-sales
Editor’s Note: This article was created by Alicia Shapiro, CMO of AiNews.com, with writing, image, and idea-generation support from ChatGPT, an AI assistant. However, the final perspective and editorial choices are solely Alicia Shapiro’s. Special thanks to ChatGPT for assistance with research and editorial support in crafting this article.

